Research and Reports in Tropical Medicine· 2021· Review
Clinical Features of Mycetoma and the Appropriate Treatment Options
- 75citations
- 2021year
Short summary
Mycetoma, a neglected tropical disease, presents with a classical triad of swelling, sinus tracts, and granules, but unusual forms exist, requiring a definitive diagnosis for appropriate treatment.
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Key points
- Mycetoma is a neglected tropical disease characterized by swelling, sinus tracts, and granules.
- It is classified into eumycetoma (fungal) and actinomycetoma (bacterial), with similar clinical presentations.
- Definitive diagnosis is crucial as treatment differs between fungal and bacterial forms.
- Current treatment combines surgical debulking with prolonged medical therapy.
AI-generated from the title and abstract; the full text is not read.
Abstract
Mycetoma is a chronic, suppurative and debilitating granulomatous infection seen mainly in tropical and subtropical areas and is now declared as a neglected tropical disease by the World Health Organization. The clinical diagnosis is usually characterized by a classical triad of localized swelling, underlying sinus tracts, and production of grains or granules, but unusual presentations are also seen. It is classified into eumycetoma caused by the fungus, and actinomycetoma caused by the bacteria. The clinical presentation of both is almost similar and a definite diagnosis is essential before starting the treatment as it differs for both. Surgical debulking followed by a prolonged course of medical therapy now forms the mainstay of treatment due to the long course of the disease and suboptimal response. This review focuses on the various usual as well as unusual clinical presentations of mycetoma, established treatment regimens as well as recent changes in the mode of administration of drugs and newer drugs for mycetoma.
The authors' abstract, as published at the source. Research and Reports in Tropical Medicine, 2021 · DOI ↗
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Field: Microbiology
MicrobiologyMedicine