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Journal of Fungi· 2022Q1

Mycetoma: Development of Diagnosis and Treatment

Xingpei Hao, Marcus Cognetti, Rhonda Burch-Smith, Emerald O’Sullivan Mejia et al.

Short summary

Mycetoma, a triad of painless swelling, sinus tracts, and discharged grains, is more common in the US than recognized, particularly among immigrants from endemic regions.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Mycetoma is characterized by painless subcutaneous swelling, multiple sinuses/fistulas, and discharged grains in pus.
  • It predominantly affects the feet (over 70% of cases) and is endemic in tropical regions.
  • The condition is likely underdiagnosed in the USA, with millions of immigrants from endemic areas potentially affected.
  • This review updates clinicians on mycetoma's epidemiology, etiology, clinical presentation, pathogenesis, diagnosis, and treatment.

AI-generated from the title and abstract; the full text is not read.

Abstract

Mycetoma describes a heterogeneous group of cutaneous and subcutaneous infections caused by either fungi (eumycetomas) or bacteria (actinomycetomas). It is characterized by a triad of clinical symptoms: painless subcutaneous tumor-like swelling, multiple sinuses and fistulas, and discharged grains in pus. This predominantly affects the feet in more than 70% of patients. It is endemic in the "mycetoma belt" regions, including Africa, South America, and South Asia. Autochthonous mycetoma is rare in the United States of America (USA). We recently reported a Latin American immigrant with eumycetoma in the State of Maryland, USA. With millions of immigrants from endemic regions, the true number of mycetomas in the USA is most likely higher than currently recognized. With the aim to raise the awareness of clinicians about mycetoma, especially dermatologists and podiatrists, we update the development of the epidemiology, etiology, clinical presentations, pathogenesis, diagnosis, differential diagnosis, and treatment of mycetoma.

The authors' abstract, as published at the source. Journal of Fungi, 2022 · DOI ↗

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Field: Microbiology

MicrobiologyMedicine