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New England Journal of Medicine· 2017Q1· Clinical trial

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

Kenneth G. Saag, Jeffrey Petersen, Maria Luisa Brandi, Andrew C. Karaplis et al.

Short summary

In postmenopausal women with osteoporosis, 12 months of romosozumab followed by alendronate significantly reduced the risk of vertebral fractures by 48% and clinical fractures by 27% compared to alendronate alone over 24 months.

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Field: Orthopedics and Sports Medicine

Orthopedics and Sports MedicineMedicine