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New England Journal of Medicine· 2014Q1· Clinical trial

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

Michael R. McClung, Andreas Grauer, Steven Boonen, Michael A. Bolognese et al.

Short summary

Romosozumab, a monoclonal antibody targeting sclerostin, significantly increased bone mineral density in postmenopausal women with low bone mass, with the 210-mg monthly dose yielding an 11.3% increase at the lumbar spine after 12 months.

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Field: Orthopedics and Sports Medicine

Orthopedics and Sports MedicineMedicine