PubMed· 2017
Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient.
- 1,762citations
- 2017year
Short summary
A patient with anti-aquaporin 4 (AQP4) antibodies, typically associated with neuromyelitis optica spectrum disorder (NMOSD), presented with unusual autonomic dysregulation, cognitive impairment, and psychosis.
AI-generated from the title and abstract; the full text is not read.
Key points
- An AQP4-positive patient with NMOSD presented with unusual symptoms: autonomic dysregulation, cognitive impairment, and psychosis.
- Brain MRI showed hyperintense T2 signals in the hypothalamus and right optic nerve.
- Symptoms and MRI abnormalities resolved after high-dose methylprednisolone treatment.
AI-generated from the title and abstract; the full text is not read.
Abstract
We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation, cognitive impairment, and symptoms of psychosis. Only a few previous cases have been described with similar psychiatric symptoms. Brain MRI showed an abnormal hyperintense T2 signal of the hypothalamus and, to a lesser extent, a minor hyperintense signal of the right optic nerve. Her symptoms and MR abnormalities improved after high-dose methylprednisolone.
The authors' abstract, as published at the source. PubMed, 2017 · DOI ↗
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Field: Pathology and Forensic Medicine
Pathology and Forensic MedicineMedicine