Endocrine Reviews· 2018Q1
Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions
- 1,130citations
- Q1SCImago
- 2018year
Short summary
Vitamin D deficiency (<50 nmol/L 25(OH)D) accelerates bone loss and fracture risk, preventable with 800 IU daily plus calcium in the elderly. Beyond bone, vitamin D signaling is implicated in cell proliferation, immune and muscle function, and metabolic health, though clinical trial evidence for extraskeletal benefits is mixed.
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Pathology and Forensic MedicineMedicine