Neurodegenerative Diseases· 2012Q3
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
- 10,400citations
- Q3SCImago
- 2012year
Short summary
Chronic exposure to amyloid-beta (Aβ) oligomers, even for as short as 10 days, significantly increases tau phosphorylation and activates GSK3 in a mouse model of tauopathy, suggesting long-lasting effects on neurodegeneration.
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