European Journal of Neurology· 2017Q1· Review
Alzheimer's disease
- 2,553citations
- Q1SCImago
- 2017year
Short summary
This review outlines current understanding of Alzheimer's disease, covering epidemiology, genetics, pathology, pathogenesis, clinical presentation, and treatment, with a focus on emerging therapeutic strategies aimed at prevention.
AI-generated from the title and abstract; the full text is not read.
Key points
- Alzheimer's disease is the most common cause of dementia and a significant global health challenge.
- The review covers epidemiology, genetics, pathology, pathogenesis, clinical presentation, and current treatment strategies.
- Enhanced understanding of Alzheimer's pathogenesis, including the preclinical phase, is crucial for developing new therapeutic approaches.
- The focus is shifting from treating symptoms to preventing the disease.
AI-generated from the title and abstract; the full text is not read.
Abstract
Alzheimer's disease, the commonest cause of dementia, is a growing global health concern with huge implications for individuals and society. In this review, current understanding of the epidemiology, genetics, pathology and pathogenesis of Alzheimer's disease is outlined, before its clinical presentation and current treatment strategies are discussed. Finally, the review discusses how our enhanced understanding of Alzheimer pathogenesis, including the recognition of a protracted preclinical phase, is informing new therapeutic strategies with the aim of moving from treatment to prevention.
The authors' abstract, as published at the source. European Journal of Neurology, 2017 · DOI ↗
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Field: Physiology
PhysiologyMedicine