Aging Cell· 2015Q1

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava, Adam C. Gower et al.

2,461citations
Q1SCImago
2015year

Short summary

Senolytic drugs selectively kill senescent cells, improving healthspan and alleviating age-related symptoms in mice, as demonstrated by dasatinib and quercetin treatments.

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Field: Physiology

PhysiologyMedicine