JAMA Psychiatry· 2019Q1· Review

Schizophrenia—An Overview

Robert A. McCutcheon, Tiago Reis Marques, Oliver Howes

1,435citations
Q1SCImago
2019year

Short summary

Schizophrenia's positive symptoms are linked to subcortical dopamine dysfunction, while cognitive and negative symptoms relate to cortical excitatory-inhibitory imbalance, with early-life factors influencing neurodevelopmental trajectories.

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Field: Psychiatry and Mental health

Psychiatry and Mental healthMedicine