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New England Journal of Medicine· 2018Q1

Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

Mark A. Socinski, Robert M. Jotte, Federico Cappuzzo, Francesco Orlandi et al.

Short summary

Adding atezolizumab to bevacizumab plus chemotherapy (ABCP) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with metastatic nonsquamous NSCLC compared to bevacizumab plus chemotherapy (BCP). Median PFS was 8.3 months for ABCP vs. 6.8 months for BCP (HR 0.62, P<0.001), and median OS was 19.2 months vs. 14.7 months (HR 0.78, P=0.02).

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Field: Pulmonary and Respiratory Medicine

Pulmonary and Respiratory MedicineMedicine