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ACS Nano· 2022Q1

pH/Glucose Dual Responsive Metformin Release Hydrogel Dressings with Adhesion and Self-Healing via Dual-Dynamic Bonding for Athletic Diabetic Foot Wound Healing

Yongping Liang, Meng Li, Yutong Yang, Lipeng Qiao et al.

Short summary

A novel hydrogel dressing, responsive to both pH and glucose, promotes healing of chronic athletic diabetic foot wounds by releasing metformin in a dual-responsive manner.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Developed a hydrogel dressing with dual responsiveness to pH and glucose.
  • The dressing facilitates localized, dual-responsive release of metformin.
  • Incorporates enhanced adhesion and self-healing capabilities.
  • Demonstrated a promoting effect on the healing of chronic athletic diabetic foot wounds.

AI-generated from the title and abstract; the full text is not read.

Abstract

. In summary, adhesion-enhanced self-healing multifunctional PC/GO/Met hydrogels with stimuli-responsive metformin release ability and easy removability have shown a promoting effect on the healing of chronic athletic diabetic wounds and provide a local-specific drug dual-response release strategy for the treatment of type II diabetic feet.

The authors' abstract, as published at the source. ACS Nano, 2022 · DOI ↗

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Field: Rehabilitation

RehabilitationMedicine