Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

Short summary

Annual multimodal screening (MMS) and ultrasound screening (USS) for ovarian cancer did not significantly reduce mortality compared to no screening in a large UK trial (n=202,638). However, excluding prevalent cases revealed a significant 20% mortality reduction with MMS over 14 years, particularly in later years (7-14).

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