Key papers in Reproductive Medicine
Pofolia’s corpus holds 56 papers from the Reproductive Medicine subfield (2012–2023). The list below starts with the most cited.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”.
Ovarian cancer statistics, 2018
CA A Cancer Journal for Clinicians · 2018 · Q1 · SJR 104.00 · FWCI 354.00 · 3,732 citations · Open access
In 2018, the US expects 22,240 new ovarian cancer cases and 14,070 deaths, with incidence and mortality rates declining significantly since the mid-1980s.
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Hormone Research in Paediatrics · 2015 · Q1 · SJR 1.00 · FWCI 323.74 · 3,102 citations · Open access
Diagnosing Polycystic Ovary Syndrome (PCOS) in adolescents is challenging because its features often overlap with normal pubertal development, necessitating caution and longitudinal evaluation.
International Agency for Research on Cancer (IARC)
Palgrave Macmillan UK eBooks · 2018 · FWCI 1355.95 · 2,816 citations · Open access
This abstract describes the International Agency for Research on Cancer (IARC) and lists research areas it supports, including hedge funds, econometrics, market microstructure, and finance. It does not present specific research findings or results.
BioMed Research International
BioMed Research International · 2022 · Q2 · 2,439 citations
BioMed Research International is a journal that publishes original research and review articles across various biomedical sciences.
A unique view on male infertility around the globe
Reproductive Biology and Endocrinology · 2015 · Q1 · SJR 1.00 · FWCI 87.27 · 2,421 citations · Open access
This study estimates male infertility rates globally by inferring male contribution from female infertility data, revealing a 20-70% distribution and 2.5-12% prevalence of infertile men, with highest rates in Africa and Central/Eastern Europe.
National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys
PLoS Medicine · 2012 · Q1 · SJR 3.00 · FWCI 58.52 · 2,355 citations · Open access
Globally, 1.9% of women aged 20-44 unable to have a live birth and 10.5% unable to have another child were recorded in 2010, with little change since 1990 except for declines in Sub-Saharan Africa and South Asia.
ESHRE guideline: management of women with endometriosis
Human Reproduction · 2014 · Q1 · SJR 2.00 · FWCI 173.31 · 2,218 citations
A new ESHRE guideline provides 83 recommendations for managing endometriosis, addressing diagnosis, pain, infertility, recurrence, menopausal symptoms, and malignancy risk.
Endometriosis
New England Journal of Medicine · 2020 · Q1 · SJR 18.00 · FWCI 174.16 · 2,164 citations
Endometriosis affects approximately 10% of women of reproductive age, causing significant symptoms like severe pain, infertility, and fatigue.
Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century
Human Reproduction Update · 2015 · Q1 · SJR 5.00 · FWCI 78.21 · 1,929 citations · Open access
Despite a global expansion of assisted reproductive technologies (ARTs), access remains severely limited in many regions, particularly sub-Saharan Africa, where infertility disproportionately impacts women. Emerging low-cost IVF initiatives offer a potential solution to improve access and mitigate gender discrimination.
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
Endocrine Reviews · 2012 · Q1 · SJR 9.00 · FWCI 73.56 · 1,916 citations
Polycystic ovary syndrome (PCOS) is a significant metabolic disorder, not just reproductive, with a substantially increased risk for type 2 diabetes, even in lean women. A key mechanism involves a post-binding defect in insulin receptor signaling, specifically increased serine phosphorylation of the receptor and IRS-1, which impairs metabolic actions without affecting mitogenic pathways.
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The Journal of Clinical Endocrinology & Metabolism · 2013 · Q1 · SJR 2.00 · FWCI 145.03 · 1,904 citations · Open access
New clinical practice guidelines recommend using the Rotterdam criteria (androgen excess, ovulatory dysfunction, or polycystic ovaries) for diagnosing PCOS, while noting diagnostic challenges in adolescents and menopausal women.
Recommendations from the international evidence‐based guideline for the assessment and management of polycystic ovary syndrome
Clinical Endocrinology · 2018 · Q2 · FWCI 189.68 · 1,825 citations · Open access
A new international guideline offers 166 evidence-based recommendations and practice points for assessing and managing Polycystic Ovary Syndrome (PCOS). It refines diagnostic criteria, reduces unnecessary testing, and emphasizes lifestyle, emotional well-being, and cost-effective fertility treatments.
Bevacizumab Combined With Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer: The AURELIA Open-Label Randomized Phase III Trial
Journal of Clinical Oncology · 2014 · Q1 · SJR 4.00 · FWCI 169.91 · 1,632 citations · Open access
Adding bevacizumab to standard chemotherapy significantly improved progression-free survival (PFS) and objective response rate (ORR) in patients with platinum-resistant recurrent ovarian cancer.
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome†‡
Human Reproduction · 2018 · Q1 · SJR 2.00 · FWCI 119.70 · 1,575 citations · Open access
A new international guideline offers 166 evidence-based recommendations for diagnosing and managing Polycystic Ovary Syndrome (PCOS), aiming to standardize care and improve patient outcomes.
Epidemiology of ovarian cancer: a review
Cancer Biology and Medicine · 2017 · Q1 · SJR 1.00 · FWCI 126.25 · 1,575 citations
Ovarian cancer is the seventh most common cancer in women globally, with epithelial subtypes showing distinct origins, risk factors, and prognoses.
The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited
Endocrine Reviews · 2016 · Q1 · SJR 9.00 · FWCI 71.08 · 1,555 citations · Open access
Polycystic Ovary Syndrome (PCOS) is revisited as a condition primarily driven by functional ovarian hyperandrogenism (FOH), where two-thirds of cases exhibit 17-hydroxyprogesterone hyperresponsiveness to gonadotropin stimulation.
ESHRE guideline: endometriosis
Human Reproduction Open · 2022 · Q1 · SJR 3.00 · FWCI 216.51 · 1,512 citations · Open access
This guideline offers 109 recommendations for diagnosing and managing endometriosis, covering pain, infertility, recurrence, and specific patient groups, based on the best available evidence.
Evaluating cell lines as tumour models by comparison of genomic profiles
Nature Communications · 2013 · Q1 · SJR 4.00 · FWCI 124.63 · 1,497 citations · Open access
Researchers identified ovarian cancer cell lines that more closely resemble actual tumour genomic profiles than commonly used lines, proposing them as superior models for cancer research.
The International Glossary on Infertility and Fertility Care, 2017
Fertility and Sterility · 2017 · Q1 · SJR 2.00 · FWCI 96.84 · 1,480 citations · Open access
The 4th edition of the International Glossary on Infertility and Fertility Care has been updated to include 348 consensus-based terms, adding 79 new definitions and modifying numerous existing ones to reflect scientific, technological, and social advancements.
Epithelial ovarian cancer: Evolution of management in the era of precision medicine
CA A Cancer Journal for Clinicians · 2019 · Q1 · SJR 104.00 · FWCI 130.39 · 1,477 citations · Open access
Epithelial ovarian cancer management is evolving towards precision medicine, integrating deep molecular profiling to tailor treatments beyond traditional surgery and chemotherapy.
Recently added
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
The Journal of Clinical Endocrinology & Metabolism · 2023 · Q1 · SJR 2.00 · FWCI 159.52 · 772 citations · Open access
The 2023 International Evidence-based Guideline for PCOS offers 254 updated recommendations, including AMH as an alternative to ultrasound for adult diagnosis, and emphasizes broader features like metabolic risks, psychological impact, and pregnancy complications.
BioMed Research International
BioMed Research International · 2022 · Q2 · 2,439 citations
BioMed Research International is a journal that publishes original research and review articles across various biomedical sciences.
ESHRE guideline: endometriosis
Human Reproduction Open · 2022 · Q1 · SJR 3.00 · FWCI 216.51 · 1,512 citations · Open access
This guideline offers 109 recommendations for diagnosing and managing endometriosis, covering pain, infertility, recurrence, and specific patient groups, based on the best available evidence.
Diagnosis and Management of Infertility
JAMA · 2021 · Q1 · SJR 5.00 · FWCI 131.32 · 1,268 citations
Infertility affects 12.7% of US women aged 15-49 annually, with 85% having identifiable causes like ovulatory dysfunction (25%), male factors, or tubal disease; 15% have unexplained infertility.
Treatment of epithelial ovarian cancer
BMJ · 2020 · Q1 · SJR 1.00 · FWCI 83.38 · 924 citations
Genetic testing for gene mutations affecting treatment is now standard for all women with epithelial ovarian cancer, alongside integrated care teams and surgical cytoreduction to R0 followed by adjuvant chemotherapy.
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