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The Lancet Oncology· 2012Q1

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies

Celeste Leigh Pearce, Claire Templeman, Mary Anne Rossing, Alice W. Lee et al.

Short summary

A pooled analysis of 13 studies (7911 invasive ovarian cancer cases) found that a history of endometriosis significantly increases the risk of clear-cell (OR 3.05), low-grade serous (OR 2.11), and endometrioid (OR 2.04) invasive ovarian cancers, but not mucinous or high-grade serous subtypes, or borderline tumors.

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Field: Reproductive Medicine

Reproductive MedicineMedicine