· 2016
Polycystic ovary syndrome
- 1,015citations
- 2016year
Short summary
Polycystic ovary syndrome (PCOS) affects ~1 in 15 women globally, characterized by excessive androgen and often abnormal insulin activity, leading to diverse health issues like infertility and metabolic syndrome.
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Key points
- PCOS affects about 1 in 15 women globally.
- Key endocrine disruptions include excessive androgen and often abnormal insulin activity.
- Health complications include menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome.
- Women with PCOS have an established increased risk of type 2 diabetes.
AI-generated from the title and abstract; the full text is not read.
Abstract
Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects about one in 15 women worldwide. The major endocrine disruption is excessive androgen secretion or activity, and a large proportion of women also have abnormal insulin activity. Many body systems are affected in polycystic ovary syndrome, resulting in several health complications, including menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. Women with this disorder have an established increased risk of developing type 2 diabetes and a still debated increased risk of cardiovascular disease. The diagnostic traits of polycystic ovary syndrome are hyperandrogenism, chronic anovulation, and polycystic ovaries, after exclusion of other conditions that cause these same features. A conclusive definition of the disorder and the importance of the three diagnostic criteria relative to each other remain controversial. The cause of polycystic ovary syndrome is unknown, but studies suggest a strong genetic component that is affected by gestational environment, lifestyle factors, or both.
The authors' abstract, as published at the source., 2016 · DOI ↗
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Field: Reproductive Medicine
Reproductive MedicineMedicine