Endocrine Reviews· 2019Q1
Endometriosis
- 842citations
- Q1SCImago
- 2019year
Short summary
Endometriotic lesions, unlike normal endometrium, show epigenetic abnormalities in stromal cells (e.g., GATA6 overexpression) and cancer driver mutations in epithelial cells (e.g., KRAS), driving estrogen production, inflammation, and progesterone resistance.
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Reproductive MedicineMedicine