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JAMA Oncology· 2015Q1

Inherited Mutations in Women With Ovarian Carcinoma

Barbara M. Norquist, Maria I. Harrell, Mark F. Brady, Tom Walsh et al.

Short summary

In a study of 1915 women with ovarian carcinoma (OC), 18% carried pathogenic germline mutations in genes associated with OC risk, including BRCA1/2 (15%) and other genes like BRIP1, RAD51C, RAD51D, PALB2, and BARD1 (3.3%).

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Field: Reproductive Medicine

Reproductive MedicineMedicine