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American Journal of Transplantation· 2012Q1

Evolution and Clinical Pathologic Correlations of De Novo Donor-Specific HLA Antibody Post Kidney Transplant

Chris Wiebe, Ian W. Gibson, Tom Blydt‐Hansen, Martin Karpinski et al.

Short summary

In 15% of kidney transplant recipients (47/315) without pre-existing antibodies, de novo donor-specific HLA antibodies (dnDSA) developed a median of 4.6 years post-transplant, significantly reducing 10-year graft survival to 57% compared to 96% in those without dnDSA.

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Field: Transplantation

TransplantationMedicine