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Journal of the American Society of Nephrology· 2017Q1

Antibody-Mediated Rejection Due to Preexisting versus De Novo Donor-Specific Antibodies in Kidney Allograft Recipients

Olivier Aubert, Alexandre Loupy, Luis Hidalgo, Jean–Paul Duong Van Huyen et al.

Short summary

Kidney transplant recipients with de novo donor-specific antibodies (DSA) at rejection show worse graft survival (34% at 8 years) compared to those with preexisting DSA (63%), despite similar C4d deposition and peritubular capillaritis.

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Field: Transplantation

TransplantationMedicine