Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

Short summary

A novel mechanism where macrophages transform into myofibroblasts drives interstitial fibrosis, a key cause of kidney transplant failure. These transitional cells constitute about half of the fibrotic cells and their numbers correlate with reduced graft function.

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