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Journal of the American Society of Nephrology· 2012Q1

Donor-Specific Antibodies Adversely Affect Kidney Allograft Outcomes

Sumit Mohan, Amudha Palanisamy, Demetra Tsapepas, Bekir Tanrıöver et al.

Short summary

Kidney transplant recipients with donor-specific antibodies (DSAs) detected only by sensitive solid-phase assays (SPAs), despite negative crossmatch results, face nearly double the risk of antibody-mediated rejection and a 76% higher risk of graft failure.

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Field: Transplantation

TransplantationMedicine