Open Medicine· 2016Q2· Review
Platelet Rich Plasma: a short overview of certain bioactive components
- 398citations
- Q2SCImago
- 2016year
Short summary
Platelet-rich plasma (PRP), derived from a patient's own blood, contains growth factors and biomolecules crucial for wound healing, but variable preparation protocols lead to inconsistent bioactive substance levels and thus modulated healing intensity.
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Key points
- PRP contains growth factors and biomolecules vital for wound healing.
- Different PRP preparation protocols yield varying amounts of bioactive substances.
- The concentration of bioactive substances in PRP can modulate wound healing intensity.
- The role of leukocytes in PRP's effect on wound healing is a subject of discussion.
AI-generated from the title and abstract; the full text is not read.
Abstract
Platelet rich plasma (PRP) represents a relatively new approach in regenerative medicine. It is obtained from patient's own blood and contains different growth factors and other biomolecules necessary for wound healing. Since there are various protocols for PRP preparing, it usually results with PRP generation with different amounts of bioactive substances, which finally may modulate the intensity of wound healing. The reference data about potential effect of some PRP compounds on wound healing, in different tissues, are still controversial. This review summarizes recently known facts about physiological role of certain PRP components and guidance for further research. Also, this review discusses different procedure for PRP generation and potential effect of leukocytes on wound healing.
The authors' abstract, as published at the source. Open Medicine, 2016 · DOI ↗
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Field: Urology
UrologyMedicine