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Skin Appendage Disorders· 2017Q2· Review

A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

Rubina Alves, Ramón Grimalt

Short summary

This review synthesizes current knowledge on Platelet-Rich Plasma (PRP), a biological product derived from a patient's own blood with elevated platelet concentration, to aid clinicians in understanding and applying this therapy.

AI-generated from the title and abstract; the full text is not read.

Key points

  • PRP is defined as autologous blood plasma with a platelet concentration exceeding baseline.
  • It is prepared from a patient's blood collected prior to centrifugation.
  • Applications in dermatology include tissue regeneration, wound healing, scar revision, skin rejuvenation, and alopecia.
  • The review aims to improve clinician understanding of PRP's biology, mechanism, and classification.

AI-generated from the title and abstract; the full text is not read.

Abstract

Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia. PRP is a biological product defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. It is obtained from the blood of patients collected before centrifugation. The knowledge of the biology, mechanism of action, and classification of the PRP should help clinicians better understand this new therapy and to easily sort and interpret the data available in the literature regarding PRP. In this review, we try to provide useful information for a better understanding of what should and should not be treated with PRP.

The authors' abstract, as published at the source. Skin Appendage Disorders, 2017 · DOI ↗

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Field: Urology

UrologyMedicine