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Molecular Psychiatry· 2016Q1· Review

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions

Nils Kappelmann, Glyn Lewis, Robert Dantzer, Peter B. Jones et al.

Short summary

Anti-cytokine treatments significantly reduced depressive symptoms by a moderate effect size (SMD=0.40) compared to placebo in individuals with chronic inflammatory conditions.

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Field: Biological Psychiatry

Biological PsychiatryNeuroscience