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Hippocampus· 2015Q2· Review

Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning

György Buzsáki

Short summary

Hippocampal sharp wave-ripples (SPW-Rs), a synchronous brain pattern, are crucial for memory consolidation and planning by replaying neuronal sequences. Disrupting SPW-Rs impairs memory, and their pathological forms ('p-ripples') are linked to epilepsy, schizophrenia, and Alzheimer's.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience