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PLoS ONE· 2016Q1

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

Kellie S. Gross, Dieter D. Brandner, Luis A. Martinez, M. Foster Olive et al.

Short summary

Activating different subtypes of group I metabotropic glutamate receptors (mGluR1a and mGluR5) in the nucleus accumbens (NAc) has opposing effects on dendritic spine density, with mGluR5 decreasing density and mGluR1a increasing it.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience