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Science· 2014Q1

Fast-spiking, parvalbumin <sup>+</sup> GABAergic interneurons: From cellular design to microcircuit function

Hua Hu, Jian Gan, Péter Jónás

Short summary

Fast-spiking, parvalbumin-positive (PV+) interneurons convert excitatory input to inhibitory output within milliseconds, thanks to highly excitable axons enabling rapid signal propagation and tight coupling of Ca2+ channels to release sensors at synapses.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience