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Annual Review of Clinical Psychology· 2014Q1· Review

Depression, Stress, and Anhedonia: Toward a Synthesis and Integrated Model

Diego A. Pizzagalli

Short summary

A new model proposes that anhedonia, a key symptom of depression, stems from impaired interactions between stress and brain reward systems, specifically mesocorticolimbic dopaminergic pathways.

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Field: Cellular and Molecular Neuroscience

Cellular and Molecular NeuroscienceNeuroscience