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International Journal of Obesity· 2014Q1

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

Arianna Psichas, Michelle Sleeth, Kevin G. Murphy, Lucy Brooks et al.

Short summary

The short chain fatty acid propionate directly stimulates the release of appetite-suppressing gut hormones GLP-1 and PYY in rodents. This effect is mediated by the free fatty acid receptor 2 (FFA2) on gut cells.

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Field: Endocrine and Autonomic Systems

Endocrine and Autonomic SystemsNeuroscience