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Nature Communications· 2014Q1

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

Gary Frost, Michelle Sleeth, Meliz Sahuri-Arisoylu, Blanca Lizarbe et al.

Short summary

Dietary acetate, produced by gut bacteria fermenting carbohydrates, crosses the blood-brain barrier and directly suppresses appetite by activating specific hypothalamic neurons.

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Field: Endocrine and Autonomic Systems

Endocrine and Autonomic SystemsNeuroscience