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Physiological Reviews· 2016Q1· Review

Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans

Stephanie Kullmann, Martin Heni, Manfred Hallschmid, Andreas Fritsche et al.

Short summary

Brain insulin resistance, a decrease in insulin sensitivity in central nervous pathways, is a shared pathological feature of metabolic (obesity, type 2 diabetes) and cognitive (aging, dementia) disorders in humans.

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Field: Endocrine and Autonomic Systems

Endocrine and Autonomic SystemsNeuroscience