Signal Transduction and Targeted Therapy· 2023Q1· Review
The blood–brain barrier: Structure, regulation and drug delivery
- 1,666citations
- Q1SCImago
- 2023year
Short summary
The blood-brain barrier (BBB) impedes drug delivery to the central nervous system, but new materials science and nanotechnology offer strategies like transcytosis, intranasal administration, and ligand conjugation to enhance brain penetration for treating CNS disorders.
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NeurologyNeuroscience