Journal of Bone and Mineral Research· 1999Q1· Review

Growth Factor Regulation of Fracture Repair

George L. Barnes, Paul J. Kostenuik, Louis C. Gerstenfeld, Thomas A. Einhorn

499citations
Q1SCImago
1999year

Short summary

Growth factors like PDGF, TGF-β, FGF, and BMPs are released at fracture sites, initiating and regulating the complex, multi-stage process of bone healing, which mirrors embryonic bone development.

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Molecular BiologyBiochemistry, Genetics and Molecular Biology