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Nature Genetics· 2026Q1

Cohesin prevents local mixing of condensed euchromatic domains in living human cells

Masa A. Shimazoe, Shiori Iida, Katsuhiko Minami, Koichi Higashi et al.

Short summary

Cohesin-mediated loops organize euchromatin into condensed domains, preventing local mixing and maintaining transcriptional insulation in human cells.

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Molecular BiologyBiochemistry, Genetics and Molecular Biology