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Pharmaceuticals· 2026Q1

Optimized Chitosan Nanoparticles for Enhanced Ciprofloxacin Delivery and Activity Against Resistant Bacteria

Lina Alharbi, Ghaida Abalkhail, Fatimah Alabrah, Faisal Alsuwayyid et al.

Short summary

Optimized chitosan nanoparticles (NPs) loaded with ciprofloxacin (CIP) demonstrated a 2-4 fold reduction in minimum inhibitory and bactericidal concentrations against resistant strains of *Staphylococcus aureus* and *Pseudomonas aeruginosa*, compared to free CIP.

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Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics