Journal of Microencapsulation· 2026Q2
Alginate-chitosan encapsulated iron oxide (Fe 3 O 4 )-sweet basil oil (SBO) nanoparticles for intestinal delivery in animal nutrition
- 0citations
- Q2SCImago
- 2026year
Short summary
Alginate-chitosan coated iron oxide nanoparticles successfully encapsulate sweet basil oil (SBO), enhancing its thermal stability and delivering it to the intestines for animal nutrition.
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Key points
- Fe3O4 nanoparticles were successfully coated with alginate-chitosan (SA-CS) for sweet basil oil (SBO) encapsulation.
- Encapsulation improved SBO's thermal stability and conferred antioxidant and broad-spectrum antibacterial activities.
- The nanoparticles released 73.79% of phenolic compounds in simulated intestinal fluid.
- Fe3O4-SBO-SA-CS effectively protected SBO activity under acidic conditions, bile salts, and during storage.
AI-generated from the title and abstract; the full text is not read.
Abstract
Nanotechnology is considered a promising approach to enhance the functionality of phytobiotics, that promote animal health. This study aimed to fabricate iron oxide nanoparticles (Fe3O4) coated with alginate (SA)-chitosan (CS) for the delivery of sweet basil oil (SBO). Fe3O4-SBO-SA-CS was characterised in terms of its physicochemical properties, safety, in vitro release, and stability. Fe3O4-SBO was successfully modified with SA-CS polysaccharides, as evidenced by Fourier transform infra-red spectroscopy. Thermal stability of SBO was enhanced by being incorporated into Fe3O4-SA-CS, whereas Fe3O4-SBO-SA-CS exhibited high antioxidant with broad-spectrum antibacterial activities against Escherichia coli, Salmonella typhimurium, and Staphylococcus aureus. The release was 73.79% with a phenolic compound content of 82.85 mg GAE/g in simulated intestinal fluid. The Fe3O4-SBO-SA-CS effectively protected SBO activity under acid, bile salt and storage. Therefore, Fe3O4-SBO-SA-CS demonstrated the potential not only to protect and deliver SBO to the target site but also to support its safe application in animal nutrition.
The authors' abstract, as published at the source. Journal of Microencapsulation, 2026 · DOI ↗
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Field: Pharmaceutical Science
Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics