Angewandte Chemie International Edition· 2012Q1· Review
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
- 2,966citations
- Q1SCImago
- 2012year
Short summary
Direct C-H bond functionalization is an emerging, powerful method for creating carbon-carbon and carbon-heteroatom bonds, offering an ideal route for synthesizing complex molecules.
AI-generated from the title and abstract; the full text is not read.
Key points
- Direct C-H bond functionalization is a powerful synthetic strategy.
- Enables formation of C-C and C-heteroatom bonds.
- Accelerates synthesis of natural products and pharmaceuticals.
- Offers an ideal and efficient route for complex molecule construction.
AI-generated from the title and abstract; the full text is not read.
Abstract
The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
The authors' abstract, as published at the source. Angewandte Chemie International Edition, 2012 · DOI ↗
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Field: Organic Chemistry
Organic ChemistryChemistry