Saudi Pharmaceutical Journal· 2012Q2· Review
Review on in vivo and in vitro methods evaluation of antioxidant activity
- 1,733citations
- Q2SCImago
- 2012year
Short summary
A review of 74 articles identified 407 antioxidant activity evaluation methods, classifying them into 19 in vitro and 10 in vivo techniques, with DPPH and LPO being the most frequent respectively.
AI-generated from the title and abstract; the full text is not read.
Key points
- Analyzed 74 articles and 407 antioxidant activity evaluation methods.
- Classified methods into 19 in vitro and 10 in vivo techniques.
- DPPH assay is the most frequent in vitro method.
- Lipid peroxidation (LPO) assays are the most frequent in vivo method.
- Ethanol is the most commonly used solvent for extraction.
AI-generated from the title and abstract; the full text is not read.
Abstract
A good number of abstracts and research articles (in total 74) published, so far, for evaluating antioxidant activity of various samples of research interest were gone through where 407 methods were come across, which were repeated from 29 different methods. These were classified as in vitro and in vivo methods. And those are described and discussed below in this review article. In the later part of this review article, frequency of in vitro as well as in vivo methods is analyzed with a bar diagram. Solvents are important for extracting antioxidants from natural sources. Frequency of solvents used for extraction is also portrayed and the results are discussed in this article. As per this review there are 19 in vitro methods and 10 in vivo methods that are being used for the evaluation of antioxidant activity of the sample of interest. DPPH method was found to be used mostly for the in vitro antioxidant activity evaluation purpose while LPO was found as mostly used in vivo antioxidant assay. Ethanol was with the highest frequency as solvent for extraction purpose.
The authors' abstract, as published at the source. Saudi Pharmaceutical Journal, 2012 · DOI ↗
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Field: Organic Chemistry
Organic ChemistryChemistry