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Circulation· 2026Q1

Intestinal Serotonergic Vagal Signaling as a Mediator of Microbiota-Induced Hypertension

Alan de Araujo, Hemaa Sree Kumar, Tao Yang, Emily otmanowski et al.

Short summary

Intestinal serotonin (5-HT) signaling via the vagal 5HT3a receptor is a crucial link between gut microbiota and blood pressure homeostasis, and restoring this signaling can alleviate hypertension.

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Molecular BiologyBiochemistry, Genetics and Molecular Biology