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Protein Science· 2026Q1

Building coiled coils with polar cores

Marcus D. Hartmann, Birte Hernandez Alvarez, Mikel Martínez-Goikoetxea, Andrei N. Lupas

Short summary

Researchers designed and structurally characterized coiled-coil sequences with extended stretches of hydrophilic residues in their core, challenging the hydrophobic nature of typical coiled coils.

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Field: Organic Chemistry

Organic ChemistryChemistry