Nature Communications· 2017Q1
In situ click chemistry generation of cyclooxygenase-2 inhibitors
- 7,562citations
- Q1SCImago
- 2017year
Short summary
Researchers developed a novel method using the cyclooxygenase-2 (COX-2) enzyme's active site as a reaction vessel to generate highly specific COX-2 inhibitors via in situ click chemistry.
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Organic ChemistryChemistry