Nature Cell Biology· 2026Q1
The Batten disease protein CLN8 is a stereospecific acyltransferase in bis(monoacylglycero)phosphate biosynthesis
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- Q1SCImago
- 2026year
Short summary
The endoplasmic reticulum protein CLN8, implicated in Batten disease, is a stereospecific acyltransferase that converts S,S-glycerophosphoglycerol into S,S-lysophosphatidylglycerol, a key precursor for bis(monoacylglycero)phosphate (BMP) synthesis.
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