Pharmaceutics· 2026Q1
Mucoadhesive Nanoemulsions for Nose-to-Brain Delivery of Dimethyl Fumarate: Development, Characterization and Proof-of-Concept In Vivo Evaluation
- 0citations
- Q1SCImago
- 2026year
Short summary
A novel mucoadhesive nanoemulsion (NE) formulation using geraniol and chitosan oleate delivered dimethyl fumarate (DMF) to the rat cerebrospinal fluid (CSF) with maximum concentrations of ~8 µg/mL for DMF and ~1.5 µg/mL for GER within 2 hours post-intranasal administration.
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