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ACS Omega· 2026Q1

Ligand Functionalization and Fe Precursor Selection Modulated the Physicochemical Properties of Fe-MOFs and Their Biological Response on Prostate Cancer and Normal Prostate Cells

Z. Durmuş, Gizem Kugu, Zihni Onur Çalışkaner, Roberto Köferstein et al.

Short summary

Synthesizing Fe-based MOFs with different iron precursors (nitrate vs. chloride) and linkers (BDC vs. NH2-BDC) alters their structure, optical properties, and biological response, with Fe-BDC-2 showing significant toxicity to prostate cancer cells (PC-3) and Fe-NH2-BDC enhancing doxorubicin (DOX) efficacy.

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Field: Inorganic Chemistry

Inorganic ChemistryChemistry