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Nature Aging· 2026Q1

A microprotein atlas of the human frontal cortex in Alzheimer’s disease

Brendan Miller, Eduardo Vieira de Souza, Calvin Lau, Joan Vaughan et al.

Short summary

Researchers created a brain microprotein (MP) atlas from over 600 frontal cortex samples, identifying 1,067 MPs not previously cataloged, with spectral evidence. A subset of these MPs are differentially expressed in Alzheimer's disease (AD).

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Field: Physiology

PhysiologyMedicine