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Biomedicine & Pharmacotherapy· 2019Q1· Review

Proanthocyanidins: A comprehensive review

Abdur Rauf, Muhammad Imran, Tareq Abu‐Izneid, Iahtisham-Ul-Haq et al.

Short summary

Proanthocyanidins, condensed tannins derived from flavonoid biosynthesis, exhibit diverse health benefits including antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial properties.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Proanthocyanidins are oligo- or polymers of flavan-3-ols.
  • They possess validated antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial properties.
  • Agricultural and food processing wastes are identified as sustainable sources for proanthocyanidins.
  • The review discusses recent developments and challenges in harnessing their health-promoting potential.

AI-generated from the title and abstract; the full text is not read.

Abstract

Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as 'offense and defense molecules because of their human health benefits. The validation of their diverse health aspects, namely, antioxidant, anticancer, antidiabetic, neuroprotective, and antimicrobial has earned them repute in thermochemistry. Proanthocyanidins are oligo- or polymers of monomeric flavan-3-ols produced as an end product of flavonoid biosynthetic pathway. Agricultural wastes and food processing wastes contain immense amount of proanthocyanidins, exploitation of which can be a sustainable source of dietary supplements and functional ingredients. The current review article discusses recent developments in the health promoting properties of proanthocyanidins and the associated hurdles.

The authors' abstract, as published at the source. Biomedicine & Pharmacotherapy, 2019 · DOI ↗

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Field: Biochemistry (Medicine)

BiochemistryMedicine