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The Journal of Organic Chemistry· 2026Q2

Stereoselective Gateway to Decorated Chloro-1,3-butadienes from Allenols via Deoxygenative 1,2-Bond Migration

P. R. SINGH, Aslam C. Shaikh

Short summary

A new strategy synthesizes E-2-chloro-1,3-butadienes from allenols via deoxygenative 1,2-bond migration, offering moderate-to-good yields and scalability.

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Abstract

Abstract We disclose an efficient strategy for the selective synthesis of E-2-chloro-1,3-butadienes from allenols. This modular approach offers an extensive substrate scope with moderate-to-good yields and operational simplicity. Additionally, they offer a versatile platform for synthetic diversification and are highly scalable.

The authors' abstract, as published at the source. The Journal of Organic Chemistry, 2026 · DOI ↗

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Field: Organic Chemistry

Organic ChemistryChemistry