Molecules and Cells· 2016Q1
Sirt1 and the Mitochondria
- 729citations
- Q1SCImago
- 2016year
Short summary
Sirt1 deacetylates PGC-1α, promoting mitochondrial biogenesis and turnover via mitophagy, which may explain its role in caloric restriction and longevity.
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Geriatrics and GerontologyMedicine