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Critical Care· 2013Q1

Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

Kianoush Kashani, Ali Al‐Khafaji, Thomas Ardiles, Antonio Artigas et al.

Short summary

Urine insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2) together detect moderate to severe acute kidney injury (AKI) within 12 hours with 80% accuracy (AUC=0.80).

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Field: Nephrology

NephrologyMedicine